what is 5-Amino-1MQ?

5-amino-1MQ is a small molecule that inhibits the activity of the enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a crucial role in metabolism and energy, primarily in fat tissue. By blocking NNMT, 5-amino-1MQ promotes an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor essential for cellular metabolism. This, in turn, boosts metabolic rate and activates a gene known as sirtuin-1 (SIRT1), also referred to as the "longevity gene." SIRT1 is involved in reducing the risk of various conditions such as diabetes, obesity, metabolic syndrome, atherosclerosis, cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.

benefits may include

  • Reduction in body fat
  • Reverse diet-induced obesity
  • Increases NAD+ and SAM concentrations in fat cells
  • Promotes lipolysis
  • Inhibits NNMT (Nicotinamide N-methyltransferase) to enhance fat cell metabolism
  • Modulates cellular energy balance
  • Promotes the metabolism of fat rather than its storage in adipocytes

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A Guide To Intermittent Fasting

Everything you need to know about Intermittent Fasting.

As one of the most effective approaches to weight control and management, intermittent fasting is quickly gaining popularity in health, fitness, and wellness circles. Several decades ago, it was used for health purposes to treat conditions such as epilepsy and diabetes. Still, many people have either never heard of it and don’t have any idea of what it is and how to do it; or they have gross misconceptions about what intermittent fasting is really about.

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