naltrexone (LDN) weight loss

what is naltrexone (LDN)?

Low Dose Naltrexone (LDN) has been used effectively for many years to treat the cravings related to drug addiction and it is now being used successfully in medical weight loss. In addition to reducing the cravings that can make it difficult to reach your weight loss goals, LDN has been shown to support the immune system, reduce inflammation, improve digestion & gut health, boost energy levels and help regulate blood sugar. LDN has not been approved by the FDA for these uses, however there are multiple studies that have shown these benefits.

Sustained-release LDN (low dose naltrexone) therapy can help to increase the dopamine levels in your brain and reduce overactive hunger cravings thereby reducing your desire to snack or overeat. Naltrexone helps to stop cravings. The dynamic relationship between naltrexone and brain receptors may help prevent thoughts of overeating or impulsive actions.

naltrexone (LDN) weight loss program at the biostation

the biostation’s Naltrexone Medical Weight loss program, uses pellets that are implanted under the skin. Pellets allow for a slow sustained release and because it does not travel through the liver, it is better absorbed.

the biostation’s 12-week LDN program includes:

• Intake session to confirm that you are a candidate for the program
• Doctor designed and supervised weight loss protocol and healthy weight management plan with weekly monitoring, based on your personalized weight loss needs
• Naltrexone pellets administered at a biostation facility
• Weekly body composition analysis to assess your body fat percentage, visceral body fat, skeletal muscle mass, metabolic rate, extracellular water weight, segmental fat analysis, obesity analysis and more
• bLean lipotropic Injections to help accelerate your body fat reduction and improve your energy
• Nutritional guides
• bCardio greens detox supplement
• bVital digestive enzymes supplement

*Post diet wellness program also available which includes bioidentical hormone therapy, heavy metal detox/chelation, and nutrient therapy

Mechanisms of Action for Weight Loss

Naltrexone's influence on appetite regulation and food cravings involves its interaction with the brain's opioid receptors. These receptors play a role in regulating both the sensation of hunger and the rewarding effects of food in the brain. High-calorie foods, particularly those high in sugar and fat, can trigger the release of dopamine in the brain, producing feelings of pleasure and reinforcing the desire to consume these foods.

Naltrexone's ability to block opioid receptors may dampen the brain's response to these rewarding stimuli, ultimately reducing cravings. For example. this preclinical study shows that naltrexone acts in hypothalamic brain regions that regulate appetite and energy expenditure while also affecting eating behaviors that are controlled by the brain's reward system.

Effectiveness of Naltrexone for Weight Loss

Several clinical trials have evaluated the weight-loss effectiveness of naltrexone, often in combination with another medication called bupropion. A National Library of Medicine study examined 242 patients of both sexes between 18 and 60 years old with a body mass index of 27-45 and found that naltrexone was effective in the weight loss of overweight participants. After 26 weeks, patients taking naltrexone and bupropion had lost 8.52% more weight than those in the control group. Some patients experienced side effects that led to the discontinuation of naltrexone, including insomnia (1.2%), dizziness (1.2%), headache (1.7%), anxiety (2.1%), and nausea (7.0%).

A different study showed that naltrexone had an influence on cortisol increases and that those with higher cortisol levels saw greater reductions in food addictions when using naltrexone. Another study showed that naltrexone may also reduce binge-eating symptoms related to obesity and major depressive disorder with results shown between four and 24 weeks after taking naltrexone and bupropion.

Safety Considerations

Naltrexone generally has a favorable safety profile. However, like any medication, it can cause side effects in some individuals. Common side effects of naltrexone include nausea, headache, dizziness, fatigue, insomnia, and gastrointestinal issues, such as diarrhea or constipation. These side effects are reportedly usually mild to moderate in severity and tend to diminish over time as your body adjusts to the medication. While naltrexone is generally well tolerated, there are certain contraindications and precautions to consider. Naltrexone should not be used if you have acute hepatitis or liver failure, as it may exacerbate liver function abnormalities.

You should also not use naltrexone if you have kidney issues or if you're taking opioid-containing medications, as it may increase the risk of overdose. Medical supervision and regular monitoring are essential to check for potential side effects and make any necessary adjustments to the dosage or treatment plan. Liver function tests may be recommended to check for signs of liver toxicity, especially during the early stages of naltrexone treatment. If you're considering naltrexone therapy for weight loss, we recommend consulting a health care provider before starting treatment, particularly if you have any underlying conditions or are taking other medications.

Incorporating Naltrexone Into a Weight Loss Plan

Incorporating naltrexone into a healthy weight loss plan can enhance its effectiveness and support sustainable weight loss. Take naltrexone as prescribed by your health care provider at the biostation, following the recommended dosage and schedule for optimal results. Incorporate regular physical activity into your routine to promote calorie expenditure and improve your fitness levels, and aim for a combination of cardiovascular exercise, strength training, and flexibility exercises for optimal results. Drink plenty of water throughout the day to stay hydrated and support your body's natural detoxification processes.

Pairing naltrexone therapy with healthy eating habits, such as consuming a balanced diet rich in nutrient-dense foods, can enhance its effectiveness. Eat plenty of fruits, veggies, whole grains, and lean proteins, and avoid processed foods, sugar, and unhealthy fats. Pay attention to portion sizes and practice mindful eating to avoid overconsumption. Chew slowly, use smaller plates, and listen to your body's hunger and fullness cues to maintain control over your calorie intake. Ultimately, adopting a holistic approach to weight management is important. This means combining medication with healthy habits for sustainable results and improving your overall well-being.

Is Naltrexone Right for You?

Naltrexone can be an effective tool for weight loss by influencing appetite regulation and reducing food cravings. When used in combination with healthy eating habits and regular exercise, naltrexone therapy can contribute to sustainable weight loss. It's essential to consult with a health care professional first to determine if it's a suitable option for you. A personalized consultation with a health care provider at the biostation in South Florida can help you make informed decisions about your health journey. Take the first step towards achieving your weight loss goals by scheduling a consultation at the biostation today.