The Effects of HRT: Men’s Bone Health and the Risk of Osteoporosis

Bone health is a serious concern among men as they age. In fact, as many as 20% of men ages 50 and older will suffer a fracture due to osteoporosis.

Men in their 50s do not generally lose bone mass as much as women during women’s menopausal years. However, by ages 65 to 70, men and women lose bone mass and experience decreased calcium absorption at about the same rate.

The resulting loss of bone mineral density can result in the weakened and fracture-prone bones of osteoporosis. For men, this is particularly dangerous. Statistics suggest men are two to three times more likely, compared to women, to die from complications of osteoporosis-related hip fractures.

Being older, Caucasian, and thin are among common risk factors for osteoporosis in men. Others include:

  • Family history of osteoporosis or personal history of fracture
  • Ongoing glucocorticoid (or steroid) medication use
  • Hypogonadism, or low testosterone
  • Hypercalciuria, or high calcium loss in urine
  • Lack of physical activity, especially weight-bearing exercise
  • Gastrointestinal disorders
  • Thyroid disorders
  • Vitamin D deficiency
  • Alcohol abuse
  • Smoking

An emerging concern for men and their bone health is estrogen deficiency. Recent research suggests an association between low estrogen levels in men and osteoporosis risk. This is an ongoing area of study.
Assessing a man’s bone health, as well as fracture and osteoporosis risks, is based on several factors, including:

  • A personal and family history
  • Risk factor analysis
  • Physical examination, including assessments of mobility, balance, and height
  • Results of a dual-energy X-ray absorptiometry (DXA or DEXA) scan, which measures bone mineral density
  • Urine and blood tests, looking for abnormal levels of testosterone, calcium, and vitamin D

Treatments for men with osteoporosis include:

  • Lifestyle changes
  • Hormone replacement therapy (HRT), including testosterone therapy
  • Bisphosphonate and other medications

While testosterone therapy has been shown in studies to increase bone mineral density in men whose testosterone levels are low, researchers have not yet determined whether testosterone therapy decreases men’s bone fracture risk.

Studies suggest lifestyle changes can promote men’s bone health and prevent osteoporosis. Lifestyle recommendations include:

  • Adequate calcium consumption through diet and supplementation
  • Vitamin D supplementation in men with low vitamin D levels
  • Regular weight-bearing exercise
  • Limited alcohol consumption
  • Smoking cessation

the biostation™ team of experts specializes in prescribing custom-designed nutraceutical therapy and bioidentical hormone replacement therapy (HRT) regimens aimed at improving not only quality of life, but also general health factors, such as bone health.

Call the biostation today at 888-754-1852 or contact us online to schedule your private, personal consultation.


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